NFL Week 10 Picks From the MMQB Staff: Eagles Visit Packers on Monday Night

Midseason Week 10 shows clear consensus on several favorites (Broncos, Colts, Bears, Bills, Seahawks, Lions), while prime-time clashes — Steelers at Chargers, Eagles at Packers, Rams at 49ers — feature splits. For bettors: back the unanimous panel picks for safer straight-up wagers, but be cautious on 4-3 and 5-2 splits (Patriots-Buccaneers, Steelers-Chargers, Ravens-Vikings, Jaguars-Texans) where injury news and momentum could swing spreads.

Week 10 overview: trade deadline done, stakes rising

The trade deadline has passed and the season sits at its midpoint. A week of games carries meaningful playoff implications, with several unanimous panel picks and a handful of tight splits that deserve close attention from bettors and fantasy managers alike.

Raiders at Broncos

Albert Breer: Broncos
Clare Brennan: Broncos
Mitch Goldich: Broncos
Gilberto Manzano: Broncos
Conor Orr: Broncos
John Pluym: Broncos
Matt Verderame: Broncos

Falcons vs. Colts (in Berlin)

Albert Breer: Colts
Clare Brennan: Colts
Mitch Goldich: Colts
Gilberto Manzano: Colts
Conor Orr: Colts
John Pluym: Colts
Matt Verderame: Colts

Giants at Bears

Albert Breer: Bears
Clare Brennan: Bears
Mitch Goldich: Bears
Gilberto Manzano: Bears
Conor Orr: Bears
John Pluym: Bears
Matt Verderame: Bears

Bills at Dolphins

Albert Breer: Bills
Clare Brennan: Bills
Mitch Goldich: Bills
Gilberto Manzano: Bills
Conor Orr: Bills
John Pluym: Bills
Matt Verderame: Bills

Ravens at Vikings

Albert Breer: Ravens
Clare Brennan: Vikings
Mitch Goldich: Ravens
Gilberto Manzano: Ravens
Conor Orr: Ravens
John Pluym: Vikings
Matt Verderame: Ravens

Browns at Jets

Albert Breer: Jets
Clare Brennan: Jets
Mitch Goldich: Jets
Gilberto Manzano: Jets
Conor Orr: Browns
John Pluym: Jets
Matt Verderame: Jets

Patriots at Buccaneers

Albert Breer: Buccaneers
Clare Brennan: Patriots
Mitch Goldich: Buccaneers
Gilberto Manzano: Patriots
Conor Orr: Buccaneers
John Pluym: Patriots
Matt Verderame: Buccaneers

Saints at Panthers

Albert Breer: Panthers
Clare Brennan: Panthers
Mitch Goldich: Panthers
Gilberto Manzano: Panthers
Conor Orr: Saints
John Pluym: Panthers
Matt Verderame: Panthers

Jaguars at Texans

Albert Breer: Texans
Clare Brennan: Jaguars
Mitch Goldich: Jaguars
Gilberto Manzano: Jaguars
Conor Orr: Jaguars
John Pluym: Jaguars
Matt Verderame: Texans

Cardinals at Seahawks

Albert Breer: Seahawks
Clare Brennan: Seahawks
Mitch Goldich: Seahawks
Gilberto Manzano: Seahawks
Conor Orr: Seahawks
John Pluym: Seahawks
Matt Verderame: Seahawks

Rams at 49ers

Albert Breer: Rams
Clare Brennan: Rams
Mitch Goldich: Rams
Gilberto Manzano: Rams
Conor Orr: Rams
John Pluym: 49ers
Matt Verderame: Rams

Lions at Commanders

Albert Breer: Lions
Clare Brennan: Lions
Mitch Goldich: Lions
Gilberto Manzano: Lions
Conor Orr: Lions
John Pluym: Lions
Matt Verderame: Lions

Steelers at Chargers

Albert Breer: Steelers
Clare Brennan: Steelers
Mitch Goldich: Steelers
Gilberto Manzano: Chargers
Conor Orr: Chargers
John Pluym: Chargers
Matt Verderame: Steelers

Eagles at Packers

Albert Breer: Eagles
Clare Brennan: Eagles
Mitch Goldich: Eagles
Gilberto Manzano: Eagles
Conor Orr: Eagles
John Pluym: Eagles
Matt Verderame: Packers

Guide to every NFL team's trade deadline: Candidates to be moved, targets who could fit, biggest needs

Betting takeaways

Back panel consensus favorites for lower-variance straight-up plays (unanimous or near-unanimous). On 4-3 and 5-2 splits, treat wagers as higher risk — shop the spread, monitor injury reports (notably the Texans’ quarterback status), and consider player props or teasers if you want exposure while limiting downside. Prime-time games with narrow panel margins are the most likely to move markets; smallest edges can be decisive.

Our writers and editors pick winners in all 14 games, including a few between top contenders.

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NFL Week 10 Picks From the MMQB Staff: Eagles Visit Packers on Monday Night

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